According to a Kotaku source (that the reported explains is not an employee of the developer, but "in a good position to know what the deal is"), the debut title from Respawn Entertainment is positioned to be a multiplayer only, and exclusive to Xbox branded consoles (from Kotaku):

The new game from Respawn is a futuristic multiplayer-centric online shooter, one of our sources says. The source describes the game as a battle of Davids and Goliaths. The Davids are heavily-armed foot soldiers. The Goliaths are the giant exosekeltons—Titans—that these soldiers can pilot. These Titans are big mech-style walkers that move with an agility not seen in games like Mechwarrior or Steel Battalions.

To keep the action balanced, game maps limit the number of Titans that can be used in a skirmish. Weapon loadouts for the foot soldiers are designed to ensure that the characters on foot can take out the Titans if need be. The source who described the game does not work at Respawn, but their description tracks with the long-reported desire by the former Infinity Ward team to make a sci-fi shooter.

As a team assembled by the co-creators of the blockbuster Call of Duty franchise, and a crew populated by many Infinity Ward veterans, details of the first title from Respawn Entertainment have been hotly anticipated. The report explains that Respawn are primarily working on the game for the yet-to-be-announced next generation Xbox console, with another studio tasked with an Xbox 360 port. Kotaku notes the possibility that it could be a timed exclusive, but is confident about the game not launching on PlayStation or Nintendo devices, and neglects to even mention the possibility of PC.

The game is being published under Electronic Arts' EA Partners label, and Respawn are widely expected to be showing the game at this year's E3 expo in June 2013.